Wayne Knight My Weight Loss Has Negatively Impacted My Career!!!

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GIVE A SKINNY GUY A SHOT!!!
TMZ.com

Wayne Knight’s health glow-up is next level ... and now he’s spilling the tea on it all, including how his weight loss has negatively impacted his Hollywood career.

We caught up with the actor at LAX on Tuesday, and he told us he’s shed a whopping 100 pounds since 1993's "Jurassic Park" -- something he's achieved by trying everything from therapy to radiation… and in true comic Wayne fashion, even "being taken by aliens."

Jokes aside, you’ve gotta watch the full video -- 'cause Wayne reveals which method actually worked best for him. Plus, he gets real about how years of yo-yo dieting have impacted him.

Amanda Bynes My Weight-Loss Journey Update!!!

Amanda Bynes is hitting some big milestones on her health journey, revealing she’s shed some of the weight she gained during her mental health struggles.

The former child star shared an IG Story post Tuesday showing her step-counter app, which tracked an impressive 14,895 steps, covering 6.6 miles and burning 481 calories -- way more than she needed for the day!

Amanda was thrilled with her progress, celebrating being down 6 pounds to 154 lbs after previously weighing 160 lbs ... following a tough period where she gained over 20 lbs due to depression.

Selena Gomez All You Body-Shamers Make Me Sick!!!

Selena Gomez came in hot, shutting down body-shamers who had the audacity to troll her look at last week’s "Emilia Pérez" premiere in L.A.

In a now-deleted TikTok post, trolls in the comments claimed Selena was "hiding" her body by posing with her hands across her stomach at the American French Film Festival -- but the actress hit back in the comments, saying it made her "sick" to see people coming for her weight.

Selena set the record straight, explaining her pose was because of a SEBO flare-up in her small intestine -- a bacterial overgrowth condition that causes bloating, pain, and other not-so-glamorous symptoms.

Lizzo Embraces 'South Park' Ozempic Joke ... Dresses as Mockery Weight Loss Drug For Halloween!!!

Lizzo's going down to "South Park" to have herself a time ... dressing up as the Ozempic alternative named after her for Halloween -- months after cracking up over the viral episode.

The singer-songwriter posted photos of her Halloween costume this year ... a box of "Lizzo" from the hit adult animated show -- with a measuring tape cinched around her waist like a belt.

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She added advertising slogans to the background ... saying Lizzo is a great way to lose guilt and gain confidence.

Christina Aguilera Nothing Spooky About This Ensemble!!! Superstar Shares Halloween Thirst Trap

Christina Aguilera is fishing for compliments with a seasonal thirst trap ... and it looks like she's continued to slim down.

The pop queen just posted a series of sultry snaps on her official Instagram page, showing off her trim physique in a Halloween inspired dress.

As Xtina explains in the caption ... it's her "favorite time of year" ... and she's got a ton of Halloween decorations around the house, even though all eyes are on her.

Not-So-Fat Joe Yeah, I Used Ozempic 💉 Helped Me Drop 200 Pounds!!!

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10:07 AM PT -- Fat Joe tells us he's been diabetic since his teenage years and Ozempic was just ONE of the countermeasures he used ... can't shortchange the years of discipline, diet, and exercise he's also applied to his health before Ozempic was even invented!!!

Unlike the dozens of celebrities suspected of secretly using weight-loss drugs, Fat Joe has no shame in his health game -- he admits Ozempic helped him drop some serious pounds!!!!

The Bronx rap legend says he also changed his diet in addition to taking Ozempic, which contributed to him losing 200 pounds.

“Ozempic says you may only have two pieces of your favorite stuff,” he tells Us Weekly -- "favorite stuff" being the carbs he had to curb.

Diddy Not So Puffy Anymore ... Lost Weight Before Arrest

Sean Combs isn't looking so puffy these days ... and not just because he changed his name from Puffy to Diddy ... he shed a bunch of pounds, but it's not a result of his time behind bars.

Diddy was looking thinner during his appearance in court Thursday and his face looked skinnier ... leading to lots of folks speculating he hasn't been eating in jail. Others thought the criminal case was finally getting to him.

However, sources familiar with the situation tell TMZ ... Diddy lost the weight BEFORE he was arrested by the feds last month, and it's the result of healthy living.

Jillian Michaels Ozempic Is A Cover-Up For Real Health Issues!!!

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OZEMPIC IS NOT THE ANSWER!!!
TMZ.com

Jillian Michaels has never sugarcoated her views on Ozempic -- but she's upping the ante, saying folks who care about their health should be seriously ticked off about the way their psychology is being exploited.

We caught up with Jillian Friday ... and she tells TMZ the weight loss drug is a distraction from real issues, pointing to the thousands of chemicals in our food that are poisoning us and making us obese in the first place.

Jillian also breaks down some stats from a recent study, pointing out how loads of people ditched Ozempic after a year -- one big reason being the weight plateau. Funnily enough, James Corden recently hinted at the same thing when he tried Ozempic himself.

James Corden I Tried Ozempic, But It Didn't Work ... Hunger Isn't Why I Eat!!!

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NOZEMPIC
This Life of Mine with James Corden

James Corden says he tried to lose weight using Ozempic, but the miracle drug didn't do much for him ... unlike lots of folks in Hollywood who are using it.

The former late-night talk show host opened up about his experience with Ozempic on his podcast, 'This Life of Mine.'

James says he tried Ozempic for a bit but it didn't help him lose weight, though it did lead to a sort of epiphany. He says it made him realize nothing about his eating habits have to do with being hungry.

38-Pound Cat Curiosity Killed the Cat ... Or, At Least Got it Stuck in A Shoe Rack!!!

Look what the cat dragged in -- a whole lot of tummy to pet diet camp ... one fat feline weighing in at a hefty 38 pounds stumbled into a hairy situation.

Crumbs -- a robust Russian cat living in a hospital on a diet of cookies and soup from the staff -- was taken to a center in Perm, where he was put on a strict diet and workout routine.

Unfortunately, Crumbs didn't enjoy his new living situation too much ... 'cause officials at the center say he tried to escape -- and, ended up stuck in a shoe rack.

ICE SPICE Feeling Spicy In Teeny Bra🔥 ... No Ozempic Needed!!!

Ice Spice's dropping a bunch of photos, bringing the heat naturally, flexing her chiseled figure in an itty-bitty lingerie set -- and shutting down any talk she's relying on the latest weight-loss craze.

A racy mirror selfie displays her killer physique -- and she's making it clear she hasn't jumped on the Ozempic bandwagon

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NO OZEMPIC FOR ME

Everyone’s buzzing over the FDA-approved prescription diabetes medication's reputation for weight-loss success -- including celebs -- but not Ice.

'1000-Lb Sisters' Tammy Slaton Livin' My Best Life ... After 500-Pound Weight Loss!!!

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SENDING POSITIVE VIBES

"1000-Lb Sisters" star Tammy Slaton has every reason to be dancing in celebration ... she just revealed she's lost 500 pounds.

The TLC personality took to TikTok on Tuesday, where she happily performed a little jig to Dylan Scott's anthem "Livin' My Best Life" ... proving she's feeling better than ever after her impressive weight-loss transformation.

The reality star showed off her new physique as she danced around her living room in shorts and a tank top. Before trolls could hate on her moves, Tammy confessed she "can't dance" ... but made it clear she's trying to spread a little joy online.

Lil Rel Howery Shows Off Drastic Weight Loss ... Doubters Say It's Ozempic!!!

Lil Rel Howery is proudly showing off his body transformation -- he's looking a lot slimmer and fitter, and some folks think he's getting a helping hand from a popular drug.

The comedian is being hounded by allegations he's using one of the weight loss drugs -- like Ozempic or Wegovy -- which are super popular these days, especially among celebs looking to shed pounds.

For his part, Lil Rel says his new look is all from diet and exercise -- specifically, he's chalking it up to 5 years of physical, mental and spiritual work on himself.

Tracy Cortez Chops Hair Off ... To Make Weight Ahead Of UFC Fight!!!

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DOING WHAT IT TAKES
UFC

Tracy Cortez pulled out all the stops to ensure she made weight for her upcoming main event fight with Rose Namajunas ... cutting off inches of her hair to come in under the 126 lb. limit!

Talk about dedication!

The 30-year-old fighter hit the scales Friday morning in Denver, CO ... with only the scale standing between her and Thug Rose, who are headlining Saturday's Fight Night card. The problem for Cortez ... she was about a pound overweight, and time was running out.

Tori Spelling O, O, O, O Tori!!! Hot Bikini Bod After Taking Weight Loss Drug

Tori Spelling is ready for hot girl summer, rocking a bikini and looking super fit ... and apparently, it's all thanks to a weight loss drug.

Tori hit the beaches of Malibu Tuesday in a neon green bikini and was kinda spilling out of her fit.

In true Malibu style, she was also rockin' some serious bling while jumping the SoCal waves.

Oprah Once Felt 'Too Fat' For Don Johnson's Christmas Party

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OVERWHELMED BY SHAME
The Jamie Kern Lima Show

Oprah Winfrey says she once didn't go to a star-studded Christmas party because she felt "too fat" to show face.

The media mogul opened up about her health journey on Tuesday's inaugural episode of the "The Jamie Kern Lima Show" ... recalling times she felt held back by public perception of her weight.

Oprah says in 1988, she was invited to Don Johnson's Christmas party ... a big deal for her at the time, considering he was starring on the hit TV show "Miami Vice."