RIP

Matthew Perry died from "the acute effects of ketamine," a drug that is used to treat depression and is also used as a recreational drug.

The Los Angeles County Medical Examiner's Office just released the toxicology report, concluding Perry had taken ketamine infusion therapy for depression and anxiety a week-and-a-half before his death. The ketamine in his system at the time of his death, however, "could not be from that infusion therapy, since ketamine's half-life is 3 to 4 hours, or less."

According to the Medical Examiner, the ketamine in Perry's system caused both cardiovascular overstimulation and respiratory depression.

The M.E. found no evidence of alcohol, methamphetamine, cocaine, heroin, PCP or fentanyl.

The contributory factors in Perry's death included drowning, coronary artery disease, and buprenorphine effects. Buprenorphine is used to ween addicts off opioids.

What's interesting ... according to the M.E., Perry had been undergoing ketamine infusion therapy every other day for some time, but 6 months before he passed, a new doctor decided Perry was doing well enough that he didn't need the treatment that often. The report does not say how frequently Perry was getting ketamine infusion therapy in the months before he died.

Although smoking was not listed as a contributing factor in Perry's death, the report notes he smoked 2 packs of cigarettes a day, had COPD/emphysema and diabetes.

And the M.E. says based on their interviews, Perry was clean and sober for 19 months.

TMZ broke the story ... on Oct. 28, Matthew was found unresponsive in his jacuzzi after playing 2 hours of pickleball at Riviera Country Club near his home in Pacific Palisades. First responders rushed to the property on a cardiac arrest call, and he was declared deceased on the scene after an apparent drowning.

While Matthew was open about his history of substance abuse, no illicit narcotics were found at his home.

Like we told you ... Matthew had played pickleball in the morning for a couple hours before returning home and sending his assistant on an errand. Sometime later, the assistant returned, discovered MP in the hot tub and then called 911.

Matthew's death sent shockwaves through Hollywood ... with tributes pouring in and tons of celebs honoring him and paying tribute.

As we first reported ... sources in daily contact with the late "Friends" star told us he had never been happier in the time leading up to his passing, committing to a new movie and loving the new home he had moved into just 3 weeks before he died there.

Matthew Perry murió a causa de "los efectos agudos de la ketamina", un fármaco que se utiliza para tratar la depresión y que también se usa como droga recreativa.

La Oficina del Médico Forense del Condado de Los Ángeles acaba de publicar el informe toxicológico, concluyendo que Perry había tomado una terapia de infusión de ketamina para la depresión y la ansiedad una semana y media antes de su muerte. Sin embargo, la ketamina presente en su organismo en el momento de su muerte "no podía proceder de esa terapia de infusión, ya que la vida media de la ketamina es de 3 a 4 horas, o menos".

Según el forense, la ketamina en el organismo de Perry causó sobreestimulación cardiovascular y depresión respiratoria.

El forense no encontró indicios de alcohol, metanfetamina, cocaína, heroína, PCP o fentanilo.

Los factores que contribuyeron a la muerte de Perry incluyen ahogamiento, enfermedad arterial coronaria y efectos de la buprenorfina. La buprenorfina se utiliza para tratar a los adictos a los opioides.

Lo que es interesante, según el forense, es que Perry había estado recibiendo terapia de infusión de ketamina durante algún tiempo, pero 6 meses antes de morir un nuevo médico había decidido que estaba lo suficientemente bien como para no necesitar el tratamiento con tanta frecuencia. El informe no indica la frecuencia con la que Perry estaba recibiendo la infusión de ketamina en los meses anteriores a su muerte.

Aunque el tabaquismo no figura como factor contribuyente a la muerte de Perry, el informe señala que fumaba dos paquetes de cigarrillos al día, padecía EPOC/enfisema y diabetes.

Y el forense dice que basándose en sus entrevistas, Perry estuvo limpio y sobrio durante 19 meses.

TMZ fue el primero en dar la noticia, el 28 de octubre, Matthew fue encontrado sin respuesta en su jacuzzi después de jugar 2 horas de pickleball en Riviera Country Club, cerca de su casa en Pacific Palisades. Los paramédicos se apresuraron en llegar a una llamada de paro cardíaco, pero el actor fue declarado muerto en la escena después de un aparente ahogamiento.

Matthew había sido muy abierto acerca de su historia con el abuso de sustancias y no se encontraron narcóticos ilícitos en su casa.

Como les contamos, Matthew había jugado pickleball por la mañana durante un par de horas antes de volver a casa y enviar a su ayudante a hacer un recado. Algún tiempo después, este regresó, descubrió al actor en la bañera de hidromasaje y llamó al 911.

La muerte de Matthew causó conmoción en Hollywood, con cientos de tributos y homenajes de diferentes celebridades para honrarlo y rendirle homenaje.

A tragedy unfolded for fans of Brazilian gospel singer Pedro Henrique ... as he collapsed onstage in the middle of a performance and died.

The incident happened Wednesday night during a religious event in Brazil, where Pedro was performing a song when he suddenly fell to the floor unconscious ... and it's all on video.

Footage shows Pedro on the edge of the stage interacting with the crowd and singing the song "Vai Ser Tão Lindo" when he appears to lose his balance ... falling backward in front of his band and crashing to the ground.

Once Pedro collapsed onstage, folks rushed over to help him as the horrified crowd watched in shock.

Pedro was rushed from the concert venue to a nearby medical clinic, where he was pronounced dead ... and his record label, Todah Music, says he suffered a massive heart attack.

He was only 30.

El cantante brasileño de gospel Pedro Henrique se desplomó en el escenario en medio de una actuación y murió.

El fatal incidente ocurrió el miércoles por la noche durante un evento religioso en Brasil, cuando Pedro estaba interpretando una canción hasta que de repente se desplomó... y todo está en video.

Las imágenes muestran a Pedro en el borde del escenario, interactuando con el público y cantando la canción "Vai Ser Tão Lindo" cuando parece perder el equilibrio, cayendo hacia atrás delante de su banda y estrellándose contra el suelo.

Una vez que Pedro se derrumbó en el escenario, la gente se apresuró en un esfuerzo por ayudarlo mientras la multitud horrorizada observaba en estado de shock.

Pedro fue trasladado rápidamente desde el lugar del concierto a una clínica cercana, donde fue declarado muerto. Su sello discográfico, Todah Music, dice que sufrió un ataque masivo al corazón.

Solo tenía 30 años.

It sounds like Naomi Osaka and Cordae have the whole parenthood thing figured out ... 'cause the tennis star says the two have made it easy by building "a really good foundation" for their baby girl.

Osaka and the "Gifted" rapper welcomed their daughter, Shai, in July ... and have been so private about raising their daughter, they don't even share photos of her on social media.

The 4-time Grand Slam singles champ briefly gave some inside info on her new role as a mother five months after giving birth ... and revealed Cordae -- who she started dating in 2019 -- is making parenting easy.

"We built a really good foundation," Osaka told InStyle this week. "I don't know if it's because he's just an easygoing guy, but I think we just respect each other's opinions. And if we disagree on something, we talk it out."

"At the end of the day, we both want what's best for Shai."

Osaka also said her pregnancy wasn't the smoothest journey -- the 26-year-old tested positive for a bacterial infection Group B streptococcus, which affects millions of expecting mothers every year.

The infection can lead to sepsis, meningitis, or stillbirth for babies ... and it made Osaka very anxious.

The death of Olympic track and field champ Tori Bowie, who was found dead as a result of childbirth complications about two months before Osaka's delivery date, had her scared as well.

"I was kind of starting to freak out a little bit," Osaka admitted. "There were so many things I wasn't aware of."

But, everything is going well now ... as Shai is a healthy baby girl, Cordae is being a great father, and Osaka -- who started back training in October -- is looking forward to the next Wimbledon and French Open.

Andre Braugher passed away following a battle with lung cancer, TMZ has confirmed.

Andre's rep tells us the Emmy-winning actor was diagnosed with the disease a few months earlier ... and he passed away Monday at age 61.

Andre was a beloved member of the TV community ... having starred in all 153 episodes of the police comedy series, "Brooklyn Nine-Nine."

His costar Terry Crews thanked Andre for his advice, kindness, and friendship in an emotional tribute after the tragic news emerged.

Andre was also known for his work on NBC's "Homicide: Life on the Street" and comedy-drama "Men of a Certain Age" -- while his movie roles included "Frequency," "The Mist," and "City of Angels."

The Julliard alum bagged 2 Primetime Emmy Awards during his celebrated career -- and on the personal front, was husband to Ami Brabson and their 3 children.

Andre Braugher falleció tras una batalla contra el cáncer de pulmón, según ha confirmado TMZ.

El representante de Andre nos dice que el actor y ganador de un Emmy fue diagnosticado hace unos meses con la enfermedad y murió el lunes a los 61 años.

Andre era un miembro muy querido de la comunidad televisiva. El actor protagonizó los 153 episodios de la serie de comedia policial, "Brooklyn Nine-Nine".

Su coprotagonista Terry Crews agradeció a Andre por sus consejos, su amabilidad y su amistad en un emotivo homenaje tras conocer la trágica noticia.

Andre también era conocido por su trabajo en "Homicide: Life on the Street" y la comedia dramática "Men of a Certain Age". Algunos de sus papeles en el cine incluyeron películas como "Frequency", "The Mist" y "City of Angels".

El ex alumno de Julliard obtuvo dos premios Primetime Emmy durante su célebre carrera y en el terreno personal estuvo casado con Ami Brabson y tuvo 3 hijos.

Pacers legend George McGinnis -- who won two ABA titles and an MVP award -- passed away on Thursday after a suffering medical emergency last week.

According to the Pacers, McGinnis -- who played for Indiana from 1971 to 1975 before the NBA merger -- died at the Community North Hospital days after he went into cardiac arrest at his home.

"We are deeply saddened to announce the passing of Hall of Famer George McGinnis," the Pacers said in a statement on Instagram.

"He was the very definition of an Indiana basketball legend, a champion, and Hall of Fame athlete. But he was more than that. George was family."

The Pacers drafted the 6-foot-8 power forward out of Indiana University ... and he quickly became a key player for Indiana's two ABA championship wins in 1972 and 1973.

He went on to become such a legend for the Pacers, the organization retired his No. 30 jersey. McGinnis is only one of only four Pacers to ever receive that honor.

McGinnis also played for the Sixers and Nuggets ... before he ended his career with the Pacers again.

"From his all-state high school days to his time as an IU All-American and, of course, to his legendary ABA championship runs with the Pacers, George McGinnis shaped so many of the fondest basketball memories for generations of Hoosiers," the Pacers said.

"A passionate advocate for his fellow ABA players and a present, smiling face around the franchise, George has been as synonymous with our Pacers franchise as anyone."

"He will be greatly missed, and all of us at Pacers Sports & Entertainment will keep George and his family in our prayers."

McGinnis was 73 years old.

Those who loved Anna 'Chickadee' Cardwell the most just had a chance to say goodbye to the reality star ... paying respects at her Georgia funeral only days after she passed away.

Members of Anna's family -- including Alana "Honey Boo Boo" Thompson and Lauryn "Pumpkin" Efird -- showed up at the Williams Funeral Home in Gordon, GA Wednesday.

Mama June and Anna's 11-year-old daughter, Kaitlyn also attended the memorial. TMZ broke the story, Mama June is now in custody of Kaitlyn following her mom's death last week.

Anna's husband, Eldridge Toney, and June's husband Justin Stroud were also in attendance.

As we first reported, the production crew for "Mama June: From Not to Hot" was documenting Anna's cancer struggles, but decided against filming the funeral services. There was also a sign outside the venue prohibiting guests from using phones inside.

As you'll recall, Anna died on Saturday due to complications from her cancer battle ... she was suffering from stage 4 adrenal carcinoma, which doctors told her was terminal.

Camden Toy, conocido por su trabajo en "Buffy Cazavampiros", ha muerto.

El actor falleció el lunes después de una batalla de dos años contra el cáncer de páncreas, esto según su página de Facebook, la cual ha sido inundada con una avalancha de fans, amigos y familiares rindiendole honores al actor fallecido.

La pareja de Camden, Bea Henderson, dijo que fue diagnosticado en febrero del año pasado "después de meses de misteriosos dolores." Y añadió: "Su estado ha empeorado mucho en los últimos dos meses y tremendamente en los últimos días", señalando que era incapaz de comunicarse hacia el final.

Ella dice que Camden decidió "por muchas razones" mantener su enfermedad en secreto, y admite que lo siente por el gran shock que ahora está llegando a los fans.

El actor Doug Jones, que trabajó junto a Camden en "Buffy", escribió: "Tantos recuerdos... trabajar juntos, décadas de risas, compartir amigos comunes, reuniones, viajes, convenciones y abrazos entre nosotros y con nuestros fans".

Además de interpretar a uno de los Gentlemen en la serie de matar vampiros, Camden apareció en varios proyectos como "Angel", "The Bay", "Average Joe", "Shameless" y "The Mentalist".

Tenía 68 años.

Camden Toy, known for his work on "Buffy the Vampire Slayer," has died.

The actor passed away Monday following a 2-year battle with pancreatic cancer ... according to his Facebook page, which has been flooded with an outpouring of fans, friends and family honoring the late actor.

Camden's partner, Bea Henderson, said he was diagnosed in February last year "after months of mysterious pain." She added, "His condition has declined a lot in the last 2 months and tremendously in the last several days," noting he was unable to communicate toward the end.

She says Camden decided "for many reasons" to keep his illness a secret ... and admits she's sorry for the big shock that's now coming to fans.

Actor Doug Jones, who worked alongside Camden on 'Buffy,' wrote, "So many memories including working together, decades of laughing, sharing mutual friends, get togethers, travel, conventions, and huggles with each other and our fans."

Apart from playing one of the Gentlemen in the vampire-slaying series, Camden appeared in various projects like "Angel," "The Bay," "Average Joe," "Shameless," and "The Mentalist."

He was 68.

Matt LeBlanc fue visto cenando esta semana, siendo uno de los últimos "Friends" en hacerlo desde que Matthew Perry murió.

El actor fue a Nobu en Malibu el martes —uno de los lugares más famosos y de alto perfil en la ciudad— quien va allí, sin duda quiere ser visto, y así fue..

Parecía bastante neutral y pensativo mientras compartía con sus amigos, y por un momento, mostró una gran sonrisa mientras saludaba a uno de sus amigos cerca del estacionamiento.

Es significativo ver a Matt finalmente de manera pública y compartiendo con sus amigos. Ya que desde el fallecimiento de su antiguo compañero de reparto que no lo veíamos en una situación así.

Hemos visto a Matt salir en público antes, pero la última vez que lo hizo, estaba al volante conduciendo por Los Ángeles.

La vida sigue adelante y también lo hacen las personas, no importa quién nos deja. Sin embargo, por muy dura que deba ser para él la muerte de Mattew, parece intentar seguir adelante con la mayor normalidad posible. Matt publicó una despedida formal a Perry el mes pasado.

Como decíamos, otros actores de "Friends" han salido a la palestra desde que Matthew falleció. Por supuesto, esto no incluye su funeral, al que todos asistieron. Hemos visto a Courteney Cox salir a cenar por Los Ángeles y David Schwimmer también ha dado la cara tras su muerte.

Los únicos que no hemos visto públicamente hasta ahora son; Jennifer Aniston y Lisa Kudrow, pero algo nos dice que es probable que las veamos por ahí a su debido tiempo también.

Matt LeBlanc stepped out for dinner this week -- one of the last remaining "Friends" to do so since Matthew Perry died ... and it's meaningful for a lot of different reasons.

The actor hit up Nobu in Malibu Tuesday -- which is big considering it's one of the most high-profile celeb hot spots in town ... and whoever goes there certainly wants to be seen. You could argue that's the case for Matt here -- who was joined by a bunch of buddies.

He looked fairly neutral and pensive as he rolled up with the boys, but at one point ... he did, in fact, flash a big smile as he greeted one of his friends near the valet booth outside.

Like we said ... it's significant to see MLB out and about like this in the wake of his old costar's tragic passing -- which occurred in late October. The reason ... they were close cast members on the hit sitcom ... just think about Chandler and Joey.

We've seen Matt step out in public before ... but the last time he did that, he was behind the wheel driving around in L.A. -- so it wasn't quite like what we're seeing here at Nobu.

The theme, you might argue, is that life moves on ... and so do people, no matter who leaves us. And yet, as hard as MP's death must be for him -- he, too, appears to be trying to carry on as normally as he can. Last month, Matt posted a formal farewell to Perry.

Like we said, other "Friends" actors have stepped out in the spotlight since Matthew passed -- not including his funeral, of course, which they all attended. We've seen Courteney Cox hit dinner in L.A. ... and David Schwimmer has also shown face in the wake of his death.

The only ones we haven't seen publicly thus far are ... Jennifer Aniston and Lisa Kudrow, but something tells us we'll likely spot them out and about in due time as well.

La batalla de Anna "Chickadee" Cardwell contra el cáncer era algo que estaba bien documentado, TMZ ha indagado y se mostrará a los fans en una próxima temporada de la serie de realidad de Mama June.

Fuentes de la familia le dicen a TMZ que Anna era muy abierta sobre sus problemas de salud y quería que se documentara en la nueva temporada de "Mama June: From Not to Hot" para que la gente pudiera entender mejor las luchas por las que pasó.

Ella también quería que los fans sepan todo lo que enfrentó, ya que siempre fue sincera con ellos.

Nos dicen que Anna no tuvo problemas con el equipo de producción filmando su viaje, la tripulación estuvo a su lado apenas unas horas antes de su muerte. Anna estaba en hospicio por un poco más de tres semanas hacia el final y estaba abierta a documentar todo.

Las fuentes dicen que la producción consideró que era mejor no estar allí en el momento final de Anna, y no estarán allí para filmar el funeral. A pesar de que Anna estaba de acuerdo, el equipo quería darle a la familia un poco de privacidad durante el duelo.

Como informamos, Anna sufría de carcinoma suprarrenal en etapa 4 y murió el sábado, nos dijeron que Anna pidió que sus fans pudieran asistir a su funeral con ataúd abierto, y nuestras fuentes dicen que la familia está honrando que como uno de sus últimos deseos.

Anna "Chickadee" Cardwell's battle with cancer was something that was well-documented, TMZ has learned ... and will be shared with fans in an upcoming season of Mama June's reality series.

Family sources tell TMZ ... Anna was very open about her health issues, and wanted it to be included on "Mama June: From Not to Hot" so people could better understand the struggles she went through, and those of cancer patients, in general.

She also wanted fans to know everything she faced, since she was always candid with them.

We're told Anna had no problems with the production team filming her journey, and the crew was by her side just hours before she passed away -- Anna was in hospice for a little over 3 weeks toward the end, and she was open to documenting everything.

Sources say production felt it was best to not be there when she passed, and they won't be there to record the funeral, either ... despite Anna being alright with it, the crew wanted to give the family some privacy while they mourn.

As we reported, Anna was suffering from stage 4 adrenal carcinoma and died on Saturday -- we were told Anna requested that her fans be able to attend her open-casket funeral, and our sources say the family's honoring that as one of her last wishes.

Andre Braugher, famous for his work on "Brooklyn Nine-Nine" and "Homicide: Life On The Street," is dead.

The longtime TV actor died Monday due to a brief illness ... according to his rep.

Andre was best known recently for starring as Captain Raymond Holt in the police comedy series "Brooklyn Nine-Nine" ... appearing in all 153 episodes alongside Andy Samberg and Terry Crews.

Terry just posted a heartfelt tribute on social media, saying ... "This hurts. You left us too soon. You taught me so much. I will be forever grateful for the experience of knowing you. Thank you for your wisdom, your advice, your kindness and your friendship."

Andre first broke through in Hollywood back in 1993, when he landed the role of Detective Frank Pembleton in the NBC drama "Homicide: Life on the Street." Andre would appear in 100 episodes of the TV show.

Andre also famously played used car salesman Owen Thoreau Jr. in the TV comedy-drama "Men of a Certain Age."

Overall, Andre earned 2 Primetime Emmy Awards among 11 nominations for his decorated TV career.

Andre also appeared on the big screen ... with roles in movies including "Frequency," "The Mist," and "City of Angels."

Born and raised in Chicago, Andre went to college at Stanford University, where he graduated with a Bachelor of Arts in theatre before continuing his studies at the Julliard School's Drama Division.

He is survived by his wife, actress Ami Brabson -- whom he married in 1991 -- and their 3 children.

Andre was 61.