John C. Reilly Good Genes or Good Docs?!

John C. Reilly's beauty is the Catalina Wine Mixer of good looks!

Here is a 27-year-old version of the comedic actor all dressed up and ready to impress at a movie premiere in Beverly Hills back in 1992 (left).

And, 28 years later ... the handsome comedian -- who is celebrating his 55th birthday today -- was last spotted looking spiffy at an event in Pasadena earlier this year (right).

This famous face is now widely known for his roles in multiple films over the years ... from voicing Ralph in Disney's "Wreck-It Ralph", to starring in iconic comedies such as, "Step Brothers," "Walk Hard: The Dewey Cox Story" and 'Talladega Nights,' he has quite the hilarious resume.

Shake and bake!

The question is ...

John C. Reilly ...

Mark Zuckerberg Good Genes or Good Docs?!

Mark Zuckerberg's looks are something to like and comment on!

Here is a 20-year-old version of the cofounder of Facebook proudly showing off his brains over brawns only 3 months after launching FB outside of Eliot House at Harvard University in Massachusetts (left).

And, 16 years later ... the father of two human daughters with his human wife Priscilla Chan -- who celebrated his 36th Earth years birthday earlier this week -- was photographed showing positive emotions and good eye contact while in Brussels for a business meeting earlier this year (right).

His timeline is updated.

The question is ...

Mark Zuckerberg ...

Teri Hatcher Good Genes or Good Docs?!

Teri Hatcher is the mother of good looks!

Here is a 28-year-old version of the actress best known for her role as the quirky single mom, Susan Mayer, on "Desperate Housewives." The actress was spotted back in 1993 rocking this short bob during an ABC press event in New York City (left).

And, 27 years later ... The now 55-year-old star -- who has a daughter of her own -- can be seen glowing with good looks, she was last spotted at a comedy show in Los Angeles, CA earlier this year (right).

These good looks are no joke!

The question is ...

Teri Hatcher ...

David Beckham Good Genes or Good Docs?!

David Beckham's good looks are truly goals!

Here is a 23-year-old version of the professional footballer showing off his fresh face during a Chelsea v. Manchester United match back in 1998 (left) ... was the same year Beckham received a red card for kicking Argentinian captain Diego Simeone, during the World Cup countdown.

And, 22 years later ... The father of four is spending this weekend celebrating his 45th birthday. He was last seen modeling his good looks for the cameras during a taping of 'The Tonight Show' earlier this year (right).

He won with these looks!

The question is ...

David Backham ...

Channing Tatum Good Genes or Good Docs?!

Channing Tatum's good looks are a magic trick!

Here is a 23-year-old version of the talented actor rockin' this buzz cut backstage at a commercial shoot as he was just starting out in the industry back in 2003 (left).

And, 17 years later ... Tatum -- who is celebrating his 40th birthday this weekend -- He was last spotted charming the crowd with his good looks at a charity event in Los Angeles earlier this year (right).

Over the years, Tatum has starred in a number of Hollywood hits, from "Step Up" and "Dear John" to "21 Jump Street" and "Magic Mike."

Oh, Dear!

The question is ...

Channing Tatum ...

Melissa Joan Hart Good Genes or Good Docs?!

Melissa Joan Hart must have a spell to keep her looking this ageless!

Here is an 18-year-old version of the "Sabrina the Teenage Witch" star showing off her wicked good looks at an award show in Los Angeles, CA back in 1994 (left).

And, 26 years later ... this actress is spending the weekend celebrating her 44th birthday.

Since her days of visiting the other realm, this glowing gal has starred in plenty of TV shows and movies including, "Melissa & Joey," "My Fake Fiancé," "No Good Nick" and much more! She was last spotted earlier this year looking better than ever at a party in West Hollywood, California (right).

Must be witchcraft!

The question is ...

Melissa Joan Hart ...

Pharrell Williams Good Genes or Good Docs?!

Will Pharrell Williams' good looks ever really die!

Here is a 29-year-old version of the Grammy award-winning artist looking his best in his signature N.E.R.D. hat at a launch party in New York City while he made waves as The Neptunes with his longtime friend and music partner Chad Hugo back in 2002 (left).

And, 18 years later ... The trendsetter is spending this weekend celebrating his 47th birthday. The BBC boss and producer was last spotted sporting his Benjamin Button looks at Paris Fashion Week earlier this year (right).

He's got a lot to be happy about!

The question is ...

Pharrell Williams ...

Reba McEntire Good Genes or Good Docs?!

The lights have never went out on Reba McEntire's beauty!

Here is a 31-year-old version of the multitalented country singer rockin' these curls at the Country Music Awards  -- where she took home the title of Entertainer of the Year -- back in 1986 (left).

And 34 years later ... Reba, who has since juggled many roles throughout her career from singing to acting on her own sitcom 'Reba,' is celebrating her 65th birthday this weekend. She was last seen looking better than ever on set of CBS's 'Young Sheldon', where she made a guest appearance as Dale's ex-wife, June (right).

Red with envy!

The question is ...

Reba McEntire ...

Keri Russell Good Genes or Good Docs?!

Keri Russell's good looks are stilled served up daily!

Here is an 18-year-old version of the actress showing off her curls at an event in Beverly Hill back in 1994 (left). This was the year Russell starred in the television series "Daddy's Girls".

And 26 years later ... This famous face has gone on to star in "The Waitress", "Dawn of the Planet of The Apes", "The Americans", and several other films and television shows. Russell is about to celebrate her 44th birthday this week and was last pictured rocking this updo at NYFW just last month (right).

It just gets better!

The question is ...

Keri Russell ...

Common Good Genes or Good Docs?!

Common's good looks are anything but common!

Here is a 33-year-old version of the multitalented star who has spent a majority of his career racking up awards, from an Academy Award to multiple Grammys and even a Golden Globe. Common has been showing off his style for years and was seen looking spiffy at Kanye West's G.O.O.D. Music Label launch party in New York City back in 2005 (left).

And, now 15 years later ... this famous face just spent this past week celebrating his 48th birthday ... prior to the big day, he was most recently seen looking like no time has passed while attending an event in New York City (right).

Glory!

The question is ...

Common ...

James Van Der Beek Good Genes or Good Docs?!

James Van Der Beek's looks are so good it's hard to trust him!

Here's the 21-year old heartthrob rising to fame as the lead, Dawson Leery, in the 1998 hit drama series "Dawson's Creek" -- starring alongside Katie Holmes and Michelle Williams -- at the NATPE Convention in New Orleans, Louisiana in 1998 (left).

And, 22 years later ... the now 43-year old father of five and "Don't Trust The B---- In Apartment 23" star -- who is celebrating his birthday today -- keeping warm as he takes a walk through the snow in Park City, Utah last month (right).

He doesn't want to wait for his life to be over!

The question is ...

James Van Der Beek ...

Rebel Wilson Good Genes or Good Docs?!

Rebel Wilson's good looks are pitcher perfect!

Here is a 21-year-old version of the "Pitch Perfect" star rockin' her curly hair at a scholarship event in Sydney, Australia back in 2002 (left).

And, 18 years later ... the now 39-year-old -- will be celebrating her 40th birthday this coming week -- was recently spotted all dressed up and out on the town in Los Angeles earlier this week (right).

Wilson has spent the last year releasing several new projects, she was featured in the film "Cats" as well as the Oscar-nominated film, "Jojo Rabbit." She also starred in a new Australian television drama, "Les Norton".

She's got it goin' on!

The question is ...

Rebel Wilson ...

Niecy Nash Good Genes or Good Docs?!

Niecy Nash's good looks are arresting!

Here is a 33-year-old version of the multitalented "Reno 911!" star showing off her flawless mug at the premiere of, "Sinbad: Legend Of The Seven Seas," in Los Angeles back in 2003 (left).

And, 17 years later ... the "Claws" cast member -- who is spending the weekend celebrating her 50th birthday -- was last spotted rockin' full glam at the Annual Essence Black Women In Hollywood Awards in Beverly Hills just a few weeks ago (right)!

Nash is currently working on Hulu's new series, "Mrs. America", which is set to release in April.

Niec and easy!

The question is ...

Niecy Nash ...

Jessica Alba Good Genes or Good Docs?!

Jessica Alba's good looks are hard not to love!

Here is a 16-year-old version of the "Valentine's Day" star rockin' this pixie cut at a movie premiere in Los Angeles, CA back in 1998 (left).

And 22 years later ... The now 38-year-old actress was last spotted looking better than ever at the Vanity Fair party in Beverly Hills, CA just last week (right).

Alba's actively working on new products for her brand, The Honest Company, and has also been busy working on a new show, "L.A.'s Finest", where she stars alongside Gabrielle Union.

L.A.'s finest indeed!

The question is ...

Jessica Alba ...

Joaquin Phoenix Good Genes or Good Docs?!

Joaquin Phoenix's good looks deserve an award of their own!

Here is a 22-year-old version of the Oscar-nominated actor showing off his slicked-back look at the Premiere of "U-Turn" in Los Angeles, CA back in 1997 (left).

And, 23 years later ... The now 45-year-old can't stop racking up the awards this season! Phoenix has been awarded best actor for his role in "Joker" several times in the past few weeks, at the Golden Globes, Critics' Choice, BAFTA, as well as the SAG awards. He was last spotted glowing with glory at a British Academy Film Awards party in London, England earlier this week (right).

He's no joke!

The question is ...

Joaquin Phoenix ...

Steve Young Good Genes or Good Docs?!

Steve Young sure did score with these good looks!

Here is a 33-year-old version of the former San Francisco 49ers quarterback and 3x Super Bowl Champion who played 15 seasons in the NFL total ... 13 of which were spent with the 49ers. Young was named the NFL's Most Valuable Player twice in his career, one of which was in 1995 after Super Bowl XXIX (left).

And, 25 years later ... the now 58-year-old athlete who now spends his time as an analyst ... was recently showing off his on-camera looks while covering the AFC wild-card playoff game (right).

He just keeps getting Young-er!

The question is ...

Steve Young ...