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Harvey Weinstein's medical issues are getting even worse because he’s now been diagnosed with leukemia, TMZ has confirmed.

The disgraced Hollywood film producer has chronic myeloid leukemia, which is a type of cancer that starts in the blood-forming cells of the bone marrow, according to the American Cancer Society.

Weinstein's rep, Juda Engelmayer, and his attorney, Arthur Aidala, declined to talk about the new diagnosis, but they issued a joint statement ... "Craig Rothfeld, Mr. Weinstein’s authorized legal healthcare representative in New York State, expresses profound dismay at the speculation surrounding Mr. Weinstein’s medical condition."

MLB fans looking to own Shohei Ohtani's historic 50/50 home run ball might need to break a few more piggy banks for it than they initially expected ... 'cause Ken Goldin just revealed to TMZ Sports it wouldn't surprise him if the baseball sold for over $10 MILLION later this week.

Currently, the memento -- which Ohtani smacked over a left field wall during a never-before-seen performance against the Marlins back on Sept. 19 -- is a few mil away from getting to eight figures ... but Goldin says it's totally possible it reaches the plateau by the time the final gavel drops on bidding on Tuesday night.

According to the auction expert -- whose auction house is actually overseeing the sale -- most bids usually come in the final hours ... and with it already being up over $2 mil, it can threaten the $10 mil threshold for sure.

Lamar Odom is recalling his own experiences with street drugs in the wake of Liam Payne's toxicology report ... telling us the substances could have made the late singer hear voices.

We got Lamar in Encino, CA and our photog asked if he had ever used the drug cocktail known as "pink cocaine" ... a mix of ketamine, methamphetamine and ecstasy that police say was found in Liam's system.

Lamar, a recovering addict who owns Odom Recovery Group, said he's done every drug Liam allegedly had in his body ... including cocaine and crack, which Lamar feels is the worst one.

American actress Gillian Jacobs was in her mid-20s when she first started playing Britta -- the smart and progressive hipster with a group of friends at Greendale Community College -- in the sitcom "Community" back in 2009.

Britta was part of an ensemble cast including Joel McHale as the former defense attorney going back to school and leader of the friend, Jeff, Donald Glover as the sensitive and goofy friend who cares deeply for his peers, Troy, and Alison Brie as the optimist gal -- super dedicated to her school, Annie.

Surfer and influencer Giulia Manfrini has died at just 36 years old ... after she was speared by a swordfish in Indonesia.

The tragic incident happened earlier this month at Masokut Island, a popular spot for surfers ... when a swordfish jumped out of the water and struck Manfrini in her chest.

Manfrini reportedly suffered a wound 2 inches deep ... and was taken to a nearby health clinic. Sadly, she did not survive.

Liam Payne had multiple substances in his system when he died in Argentina, including a mix of drugs known as "pink cocaine" ... according to the initial results from his autopsy.

Law enforcement sources in Buenos Aires tell TMZ ... the toxicology results for the late One Direction singer are in, and they show he had cocaine and crack in his body when he fell to his death from a third-floor balcony at a Buenos Aires, Argentina hotel.

Forensic examiners, we're told, also found "Cristal" in his blood, which is the Argentinian version of methamphetamine. ABC News first reported the news, adding that ketamine, ecstasy and "pink cocaine" were also part of the drug cocktail in his system.

Autumn Crittendon of "16 & Pregnant" fame died from a combination of drugs that sadly took her life ... TMZ has learned.

According to the Virginia Department of Health, the late reality star's official cause of death was toxicity from fentanyl and para-fluorofentanyl ... an illicit synthetic opioid similar to fentanyl.

The agency lists Autumn's manner of death as accidental.

Donald Trump is remembering Arnold Palmer for something other than golf or a refreshing beverage ... his huge penis.

The presidential candidate couldn't stop talking about Arnold's manhood over the weekend during a campaign rally in Palmer's hometown of Latrobe, PA ... claiming the golf legend was hung like a horse.

So naturally, we talked about it today on "TMZ on TV" ... and Trump's story about Arnold in the shower came as news to all of us.

Justin Bieber is thinking of Liam Payne and his fans in the days following the One Direction alum's death ... encouraging those who love the singer to grieve as they see fit.

The pop star posted on his Instagram Stories Monday, where he addressed Liam's passing by sharing a fan video featuring the many vigils assembled in LP's honor.

A caption on the clip read ... "Rest Easy Liam."

Cops in Argentina are digging deep to get answers in Liam Payne's death, and TMZ has learned they're questioning all the employees at the hotel where he fatally fell from his third-story balcony.

Law enforcement sources in Buenos Aires tell TMZ ... cops are focusing on one hotel employee in particular who they suspect might have supplied the late singer with anti-anxiety meds reportedly found in Liam's room at the CasaSur Palermo Hotel.

We’re told police are investigating to determine whether the employee supplied Liam with any of the drugs found in his system -- including cocaine, crack, ketamine, ecstasy and a form of crystal meth called "cristal" -- according to initial autopsy results.

Barry Keoghan and Sabrina Carpenter are still boo'd up ... and he's giving her a very public show of support amid persistent breakup rumors.

The Irish actor was spotted over the weekend at Sabrina's Sunday concert in Charlottesville, VA ... the latest evidence the couple is still going strong.

Barry had a front-row seat to watch Sabrina do her thing on her "Short n' Sweet" tour.

Diddy's reputation is so toxic nowadays, no one in Hollywood wants to be associated with him -- and any celebs linked to his parties or allegations will likely pay up to avoid being named in a lawsuit ... so says an expert in crisis public relations.

Evan Nierman, CEO of crisis PR firm Red Banyan, joined us Monday on "TMZ Live," and we asked what his advice would be to the celebs in danger of being named as defendants alongside Diddy in civil lawsuits.

One of the latest lawsuits against Diddy references two unnamed celebrities, and Evan says those famous people, whoever they are, would be wise to cut a check to the plaintiffs and their attorney Tony Buzbee ... to avoid having their names linked to Diddy.

Snoop Dogg is proving he can still drop it like it's hot, despite being well into his 50s ... making it rain at a local strip club.

The rapper rang in his 53rd birthday at his wife Shante Broadus' strip joint The Players Club in Los Angeles Sunday evening ... where he was given a legend's welcome while surrounded by friends and fans.

Check it out ... Snoop's name day was a lively affair, with multiple exotic dancers showing off their twerk skills for the rap mogul as money rained down on the event.

2:23 PM PT -- Ariana Grande is issuing a public apology to Elvira after the Mistress of the Dark called out the pop star for some alleged bad behavior many years ago.

After Elvira's criticism went viral, with the TV personality even sharing one article about the drama on her Instagram feed, the singer took to the comments and shared her side of the story.

She wrote ... "i’m so disheartened to see this. i actually don’t even remember getting the chance to meet you because i had an anxiety attack and to my memory, left before the rest of my family (this was around 7 years ago and at the time i was really not great with being in public crowds or loud places)… but if i’m misremembering this moment, i sincerely apologize for offending you so."

Polo G has been behind bars since Saturday after police claimed they found a loaded gun in his car -- and immediately arrested and hauled the "Hood Poet" off to jail!!!

Law enforcement sources tell TMZ Hip Hop cops pulled over Polo for speeding in the San Fernando Valley Saturday afternoon.

After searching his vehicle, we're told LAPD officers discovered the loaded pistol, so they cuffed him and booked Polo for felony possession of a concealed weapon.

Matthew McConaughey is NOT "alright, alright, alright" with Texas fans throwing junk on the field during Saturday's game against Georgia ... telling students to "clean that kind of BS up" and do better moving forward.

As we previously reported, UT got hit with a $250k fine for hurling bottles and debris after a controversial pass interference call in the third quarter of the matchup ... which briefly delayed the action at Darrell K Royal-Texas Memorial Stadium.

The actor -- who also serves as the Minister of Culture for all things UT-related -- was not happy with how things unfolded ... releasing a statement directed at the student body.