Christina Applegate Uses 'FU MS' Cane At SAG Awards, Possibly Last Ceremony

Christina Applegate was a standout at the SAG Awards Sunday ... not because of her nomination --- but because of her courage.

The awesome actress -- if you have any doubts, watch "Dead to Me" -- is dealing with her multiple sclerosis diagnosis, and showed up with a cane with a powerful message.

As she entered the Fairmont Century Plaza in Century City, CA with her 12-year-old daughter Sadie, she was clutching a cane with the initials, "FU MS."

Christina was up for Outstanding Performance by a Female Actor in a Comedy Series ... she said earlier this month it likely would be "my last awards show as an actor probably, so it's kind of a big deal."

As we reported, Christina revealed her multiple sclerosis diagnosis back in 2021 ... calling it a "strange journey," but one she's on with the support of others that share her condition.

She also dragged the disease late last year when she got her star on the Hollywood Walk of Fame -- flashing her painted nails with "FU MS" emblazoned on them.

Unfortunately, Christina didn't take home gold at the SAG Awards, but the outpouring of support she's been receiving has been heartwarming.