'Blow' Inspiration George Jung Died of Kidney Failure, Death Certificate Shows

George Jung -- the prolific cocaine smuggler portrayed by Johnny Depp in the film "Blow" -- died of kidney failure due to advanced liver disease, and as you'd probably imagine ... his hard-living played a major role.

According to George's death certificate ... George's immediate cause of death is listed as hepatorenal failure due to alcoholic cirrhosis. In other words, his organs succumbed to his chronic alcohol abuse. The manner of death is listed as natural causes.

George died on May 5 in Lowell, MA, and he was cremated 2 days later. Interestingly, his occupation is listed as storyteller/teacher/education. If you've seen the movie, that's not entirely inaccurate.

TMZ broke the story ... George had been experiencing kidney and liver problems before his death. He had been in home hospice care and died with his wife, Ronda, and friend, Roger, by his side.

George served 20 years in prison for running drugs for the Medellin Cartel. He was known as "Boston George" and infamously helped notorious drug lord Pablo Escobar smuggle planeloads of coke into the U.S.

At the time, Escobar's cartel was reportedly responsible for 80% of the world's cocaine.