'Storage Wars' Bargain Hunters Thrift Store Burglarized Again

"Storage Wars" star Rene Nezhoda is having a bad case of déjà vu -- his store was burglarized, again ... and this time the crooks made off with thousands in merch, again.

So here's the deal, Rene and his wife, Casey -- owners of the Bargain Hunters Thrift Store featured on the show -- say they were enjoying a day off back on February 17 when they were notified that a couple of thieves were ransacking the San Diego area store.

We’re told surveillance camera footage shows the burglars entered through a back door after smashing the glass. When the dust finally settled ... we're told they made off with tons of sports memorabilia cards and other collectibles worth between $7k-$8k.

On top of that ... Rene, Casey and their crew say the store was a disaster -- physical damages only ran 'em about $1,500, but it took a long time to clean up the mess.

Two things to note ... Rene says the burglars missed out on some VERY expensive trading cards, and thinks one of the thieves left behind some possible evidence. DOH!!!

A spokesperson for the San Diego County Sheriff's Department tells TMZ ... detectives are in the initial phase of the investigation, but are working a few leads they've developed since the heist. They have not identified the suspects yet