Megan Mullally -- Good Genes or Good Docs?!

Megan Mullally's good looks are no joke!

Here's a 41-year-old version of the "Will and Grace" star in New York City back in 1999 (left) and 19 years later ... The now 60-year-old SAG Awards host all dolled up in Beverly Hills earlier this month (right).

Award-winning!

The question is ...