'Sopranos' Star Frank Pellegrino Dead at 72 (PHOTO GALLERY)

Frank Pellegrino -- best known for his role as the FBI Chief gunning for Tony Soprano on the HBO hit show -- died after losing his battle with cancer.

Frank -- who also co-owned the popular Italian restaurant Rao's in East Harlem -- died in New York Tuesday. The restaurant, founded in 1896, was famous for celebrity drop-ins ... including Martin Scorsese, Woody Allen and Jay Z.

Frank appeared in "Goodfellas" and 'Law & Order' but he burst onto the scene beginning in 1999 when he was tapped as FBI Chief Frank Cubitoso on 'Sopranos.'

He was 72.