The Game Says 'F*** Meek Mill'

The Game kicked Russell Simmons' peace talks to the curb ... publicly dissing Meek Mill Thursday night near his hometown.

You hear Game say at the beginning of the club, "F*** Meek Mill."

Russell Simmons might have thought he shut it down, but their beef is alive and well.

BTW ... after the concert Game sauntered around Philly ... clearly not concerned about retribution.