Master P: Big Crush ... On World's Tiniest Stripper

Looks like someone's ready to go down ...

The premiere episode of Master P's new Playboy Radio show "Doin Tha Most" went off with a bang -- because P nearly banged his co-host Sassee Cassee, the world's smallest stripper.

We got video of the taping and let's just say the sexual chemistry is palpable, and a little uncomfortable -- especially when P's co-host, J Tweezy, starts talking size ... and not Sassee's.

But hey, Master P is single and as Cassee says ... once you go small, you never go tall.