Jerome Bettis -- Be Careful LeSean McCoy ... All Girl Party Too Much for One Man (VIDEO)

LeSean McCoy could be in over his head ... according to Jerome Bettis who says Shady's "females only" bash sounds like a great idea ... but only IF the Bills RB is well rested.

We broke down McCoy's plans for Sunday night with the Bus -- he's not hating on it and thinks there's very little down side. As he put it, "You gonna have a good time, I don't know about everybody else."

Check the clip -- Bettis thinks the buddy system might be in order.