Eva Longoria and Mark Sanchez Split

NY Jets QB Mark Sanchez has just lost his best wide receiver ... Eva Longoria.

Eva's rep has confirmed ... the two have officially called it quits after several months of dating.

Chalk up another loss for Sanchez (25 years old) -- who already took a beating from the Patriots this weekend.

As for Eva (37 years old) ... at least she won't have to remove any body ink from her body this time.