Miss Cleo Dead at 53

There won't be any more calls to Miss Cleo ... the iconic TV psychic is dead after battling cancer ... TMZ has learned.

A rep for Miss Cleo -- whose real name was Youree Harris -- tells us she died Tuesday morning in Palm Beach County, FL. We're told she was recently hospitalized, but was discharged last week to a hospice center.

We're told Cleo was originally diagnosed with colon cancer ... but it spread to her liver and lungs.

The rep said Cleo remained a "pillar of strength" during her illness ... and died surrounded by family and friends.

Cleo's Jamaican character and her psychic commercials became a cult classic in the late '90s ... thanks to her catchphrase, "CALL ME NOW!"

Miss Cleo was actually born in L.A. -- she just nailed the accent.

After the Psychic Readers Network closed shop, Cleo bounced around to various jobs ... including voicing a character in the video game, "Grand Theft Auto: Vice City."

R.I.P. NOW!